Ketosis-Prone Type 2 Diabetes Mellitus and <emph type="ital">Human Herpesvirus 8</emph> Infection in Sub-Saharan Africans
نویسندگان
چکیده
منابع مشابه
Insulin action in ketosis-prone diabetes Multi-tissue insulin resistance despite near-normoglycemic remission in Africans with ketosis-prone diabetes
Department of Diabetes and Endocrinology, 2 INSERM, Clinical Investigation Center CIC9504, Unit of Transfer in Molecular Oncology and Hormonology, and Department of Radiology and Medical Imaging, Saint-Louis Hospital, Assistance Publique Hôpitaux de Paris, University Paris-Diderot Paris-7, INSERM UMRS 872, Cordeliers Research Center; Paris, France UMR1019, University of Clermont 1, CRNH-Auvergn...
متن کاملSyndromes of ketosis-prone diabetes mellitus.
Ketosis-prone diabetes (KPD) is a widespread, emerging, heterogeneous syndrome characterized by patients who present with diabetic ketoacidosis or unprovoked ketosis but do not necessarily have the typical phenotype of autoimmune type 1 diabetes. Multiple, severe forms of beta-cell dysfunction appear to underlie the pathophysiology of KPD. Until recently, the syndrome has lacked an accurate, cl...
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Ketosis-prone type 2 diabetes is a unique and underrecognized clinical entity characterized by new adult onset of diabetes with severe hyperglycemia and ketosis similar to type 1 diabetes, but with clinical and biological features typical of type 2 diabetes (1). Hyperglycemic crisis with ketosis in these individuals appears to be related to acute and reversible b-cell dysfunction with subsequen...
متن کاملUpdate on diagnosis, pathogenesis and management of ketosis-prone Type 2 diabetes mellitus.
Diabetic ketoacidosis (DKA) has been considered a key clinical feature of Type 1 diabetes mellitus; however, increasing evidence indicates that DKA is also a common feature of Type 2 diabetes (T2DM). Many cases of DKA develop under stressful conditions such as trauma or infection but an increasing number of cases without precipitating cause have been reported in children and adults with T2DM. S...
متن کاملEvaluation of Genome Wide Association Study Associated Type 2 Diabetes Susceptibility Loci in Sub Saharan Africans
Genome wide association studies (GWAS) for type 2 diabetes (T2D) undertaken in European and Asian ancestry populations have yielded dozens of robustly associated loci. However, the genomics of T2D remains largely understudied in sub-Saharan Africa (SSA), where rates of T2D are increasing dramatically and where the environmental background is quite different than in these previous studies. Here,...
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ژورنال
عنوان ژورنال: JAMA
سال: 2008
ISSN: 0098-7484
DOI: 10.1001/jama.299.23.2770